Monday, December 6, 2021

ਵਾਹਿਗੁਰੂ

spot_img
yes punjab punjabi redirection

Lokan Da Channi

Channi 8

Bijli Bill

36000

Sada CM

Hunarmand

Mera Ghar

Kisan Karza

ECI Voter Form

ECI Voter Helpline

ECI Voter

Markfed Sept to Nov

Innokids Green

How Covid affects pregnant mothers and babies

- Advertisement -

New York, Nov 25, 2021- Covid-19 infection during pregnancy leads to distinct immune changes in mothers and babies, according to a study.

The researchers found that Covid-19 dysregulates maternal immune response, with different immune signatures between mothers with asymptomatic and severe disease.

“We know that pregnancy increases maternal risk for Covid-19, but relatively little is known about the long-term consequences of in-utero exposure for infants,” said Jae Jung, Director of the Cleveland Clinic Global Center for Pathogen & Human Health Research.

The study highlights “how important it will be for long-term follow-up after pregnancy to catch and hopefully prevent any unforeseen long-term health conditions related to prenatal infection,”Jung added.

For the study, published in the journal Cell Reports Medicine, the team involved 93 mothers with Covid-19 and 45 of their infant children who were exposed to SARS-CoV-2, the virus that causes Covid-19.

The research team studied immune profiles for more than 1,400 cytokines and other inflammatory proteins collected from peripheral and cord blood samples.

The researchers compared maternal blood specimens collected close to the initial detection of SARS-CoV-2 and at different time points throughout pregnancy and delivery.

They found that compared to mild or moderate disease, pregnant women with severe Covid-19 exhibited significantly more inflammation and elevated levels of a protein called IFNL1 (interferon lambda 1) and the receptor it binds with, IFNLR1, which plays a critical role in protecting against viruses.

“This increase in interferon lambda signaling may help explain why we see relatively little direct transmission of Covid-19 between mother and baby during the period right before or after birth — what we call vertical transmission,” explained Suan-Sin (Jolin) Foo, a research associate in Dr. Jung’s lab and co-first author on the paper.

Despite the lack of evidence for robust vertical transmission, the researchers found that SARS-CoV-2 infection alters maternal immunity at delivery and that gestational SARS-CoV-2 exposure alters infant immunity at birth.

At delivery, the women exhibited dysregulated levels of several cytokines that are associated with pregnancy complications, including MMP7, MDK, ESM1, BGN and CD209.

Among infants, prenatal exposure induced the expression of cytokines related to T cells, which are a type of immune cell involved in recognising and attacking specific antigens.

The majority of births within the cohort were healthy, but there was a high incidence of some complications, including preeclampsia and foetal growth restriction.

More research will be necessary to understand the extent to which the observed immune changes are related to these clinical outcomes, the team said.  (Agency)

Subscribe to YesPunjab Telegram Channel & receive important news updates

- Advertisement -

Yes Punjab - TOP STORIES

Punjab News

Sikh News

Transfers, Postings, Promotions

- Advertisement -spot_img

Stay Connected

20,369FansLike
113,088FollowersFollow

ENTERTAINMENT

National

GLOBAL

OPINION

India China Flag

India and China in the emerging geopolitics – by DC Pathak

Advent of Biden Presidency with its resonating calls of 'America is back', 'we will repair our alliances' and 'will engage with the world once...
China Flag

Globally active China – by Asad Mirza

The aggressive and planned manner in which Chinese companies have forayed globally, poses a risk not just to the economic interests but also the...
Taliban Fighters

The ‘Good’, the ‘Bad’ and the ‘Deobandi’ Taliban – by Asad Mirza

While an effort to classify the Taliban into good and bad is rather easy, the underlying reasons to classify them as Deobandi becomes a...

SPORTS

Health & Fitness

Heart Disease

Elevated heart rate may up dementia risk among older

London, Dec 4, 2021- Having an elevated resting heart rate in old age may be an independent risk factor of dementia, a new study suggests. The study, published in the journal Alzheimer's & Dementia, showed that individuals with a resting heart rate of 80 beats per minute or higher on average had a 55 per cent higher risk of dementia...

Gadgets & Tech